Specialists in Clinical and Health Services Research in the Immunocompromised Host
Interested in undertaking research with us?
We have a range of training pathways available.
Our Research
Febrile Neutropenia
Read about all our latest Febrile Neutropenia work including Guidelines, Toolkits and the latest in using Pet/CT scan to diagnose fungal infection in high risk groups.
Infection Surveillance
We are using AI, Natural Language processing and Machine Learning to build software that integrates into the EMR to detect infections in the healthcare setting in near real time.
The Microbiome
Our guts are populated by microorganisms that influence our health in many ways including responses to cancer chemotherapy and transplant. The HOMISPEC trial is profiling the microbiome of Haematology patients and patients undergoing stem cell and liver transplants.
NCIC KIDS
“Children are not small adults!” At least not as far as their immune systems are concerned. Treatment and management of infections in children affected by cancer is very different to the adult population. NCIC Fellow A/Prof Gabrielle Haeusler leads a Paeds Infection in Cancer research group at MCRI.
Antibiotic Allergy delabelling
Antibiotic allergies come and go. We contribute to research looking at ways to remove allergy labels from cancer patient files- thus allowing more appropriate antibiotic use. NCIC Fellow Prof Jason Trubiano leads the Antibiotic Allergy De-labelling Research program at the Centre for Antibiotic Allergy and Research, Austin Hospital.
CRISPR Diagnostics
In collaboration with the Cell Death and Infection lab at the WEHI, headed by Dr Marcel Doerflinger, we are investigating a novel POC test to diagnose infections at the bedside using CRISPR-Cas9 technology.
Sepsis
Sepsis can cause organ failure, making it a time critical emergency that disproportionately adversely affects cancer patients. We have developed a clinical pathway specifically for cancer patients and perform continuous Health Services and Implementation Science research into its use.
Infection Prediction
Forewarned is forearmed. We are performing research into determining an immune signature that can predict an individuals risk of infection prior to beginning cancer therapies so that we can put in place strategies to manage those infections before they interfere with treating the cancer.
Response to Vaccination
Vaccinations are especially important in cancer patients where immune responses are suppressed. NCIC Fellow A/Prof Ben Teh leads the Vaccine Response Research group at Peter Mac.
Antimicrobial Stewardship
Antibiotic resistance is on the rise due to widespread overuse. Antimicrobial Stewardship programs aim to reduce inappropriate prescribing. We are world leaders in AMS Health Services Research and Implementation Science.