Information for Providers
the intersection of Infectious disease and cancer
The National Centre for Infections in Cancer serves as a comprehensive resource for providers who care for cancer patients and cancer survivors with the goal of promoting a greater understanding of the impact of infectious diseases in this era of novel cancer therapies, ageing populations and decentralised care.
Need more information? We have extensive experience in implementing specialist clinics (eg allergy de-labelling, vaccinations) and pathways (eg sepsis pathway, low risk febrile neutropenia). Get in touch with our experts to discuss further.
Allergy clinic REFERRAL
Have a patient with allergies?
Click below for the allergy clinic referral form
How can I best care for my patients?
Low risk: "No place like home" is an ambulatory management program for patients at low risk of neutropenic fever. We have developed an implementation tool kit to assist health care workers in implementing this program at their own centres. Please ensure that they are appropriately adapted for your centre following multi-disciplinary stakeholder consultation.
Moderate to high risk: We have put together the Australian consensus guidelines for the management of neutropenic fever in adult cancer patients. Click below for the full set.
Immunotherapies and molecular targeted agents
Infections associated with immunotherapeutic and molecular targeted agents in hematology and oncology. A position paper by the European Conference on Infections in Leukemia (ECIL)
Safety of novel cancer therapies: Infectious diseases perspective
The ESCMID study group for Infections in Immunocompromised Host consensus document series for safety of targeted and biological therapies: an infectious diseases perspective
We have put together a comprehensive set of guidelines for the use of antifungals in cancer patients with the Australian and New Zealand Consensus Guidelines for the Use of Antifungal Agents in the Haematology / Oncology Setting, 2014. Click below for the complete set.
Also available are the current European Conference on Infections in Leukaemia guidelines for primary antifungal prophylaxis in adult haematology patients.
or download the free PDF of the book Fungal Infections in Immunocompromised Host edited by Dimitrios P. Kontoyiannis and Monica Slavin
Does your patient have Hepatitis B virus?
All patients with chronic HBV infection are at risk of reactivation during immunosuppression with chemotherapy.
DOWNLOAD THE AUSTRALIAN RECOMMENDATIONS FOR THE MANAGEMENT OF HEPATITIS B IN CANCER THERAPY: A CONSENSUS STATEMENT HERE
Click below for Peter MacCallum guidelines on how to manage HBV infection and cancer.
How to prevent, diagnose and treat Pneumocystis jirovecii infection (PJP)
Pneumocystis jirovecii infection (PJP) is a common cause of pneumonia in patients with cancer-related immunosuppression. Appropriate PJP prophylaxis can reduce the occurrence of PJP in high risk populations by up to 90%. Click below to view the Peter MacCallum guidelines on preventing PJP in cancer patients. Also available are the latest European Conference of Infections in Leukemia (ECIL) guidelines on PJP diagnosis and treatment in patients with haematological malignancies and stem cell transplant recipients.
TB risk may only be identified by careful history taking and must be done prior to consideration of chemotherapy, radiation therapy and surgery. Click below to view Peter MacCallum processes for identifying and managing cancer patients with active or latent TB.
BK polyomavirus-associated haemorrhagic cystitis
BK polyomavirus-associated haemorrhagic cystitis (BKPyV-HC) is rare in haematology patients other than those undergoing allogeneic HSCT. When it does occur, it is in 8%-25% of paediatric and 7%-54% of adult recipients undergoing allogeneic HSCT. Haemorrhagic cystitis contributes to post-HSCT morbidity by prolonging hospital stay and severely worsening the quality of life. The European Leukaemia Network, the Infectious Diseases Working Party of the European Association for Blood and Marrow Transplantation (IDWP-EBMT), the Infectious Disease Group of European Organization for Research and Treatment of Cancer, and the Immunocompromised Host Society (ICHS) joint initiative have just published the latest guidelines for management of BK polyomavirus-associated haemorrhagic cystitis.